Distractability

A distracted mind is an unhappy mind.

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47% of US adults surveyed were not paying attention in their waking hours. 

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(Harvard Gazette, 2010)

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Social isolation

Loneliness is a significant predictor of well-being, and is comparable to risk factors such as smoking and obesity to heart disease.

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Valtorta NK, Kanaan M, Gilbody S, Ronzi S, Hanratty B. Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies. Heart. 2016;102(13):1009–1016.

Loss of purpose

A lack of meaning or direction in life has a significant negative impact on one's well-being.  

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Cohen  R, Bavishi  C, Rozanski  A.  Purpose in life and its relationship to all-cause mortality and cardiovascular events: a meta-analysis.  Psychosom Med. 2016;78(2):122-133.